Endostatin is an independent risk factor of graft loss after kidney transplant

Researchers have identified the endothelial basement membrane biomarker endostatin that can better predict the risk of graft loss in kidney transplant recipients (KTRs) in a prospective observational cohort study with 574 maintenance KTRs (median follow-up 48 months).

“.. increased serum endostatin concentrations at baseline are independently associated with the risk of graft loss in prevalent KTRs. Its association with graft loss seems to be even stronger as compared to the established classical risk factors for graft loss: decreased GFR and increased urinary protein excretion.“ [reference]

Human endostatin can easily be measured by Biomedica's fully validated Human Endostatin ELISA.