4' video to set up cAMP assays with HTRF

A protocol video from Cisbio Bioassays (HTRF®) to introduce you to cAMP assays with HTRF® technology. Watch this video to learn about utilizing a streamlined, no wash, add and read HTRF® cAMP assay kit to monitor GPCR activation.

Features
• A presentation of the kit and assay principle
• Explanations and illustrated guidelines
• Results interpretation

Alternative Protocol for Mercodia Glucagon ELISA

The Mercodia Glucagon ELISA is highly specific and shows very low cross-reactivity to oxyntomodulin and glicentin.

But, under certain conditions like
• Post bariatric surgery
• Kidney disease
• Exogenous administration

…the levels of glicentin(1), proglucagon 1-61(2) and oxyndomodulin can be elevated to levels that interfere in the Glucagon ELISA. To avoid these interferences, an alternative protocol has been developed.

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Three outstanding application notes to discover the HTRF α-tubulin housekeeping kit

α-tubulin proteins are commonly used for housekeeping, and measuring their levels is crucial for determining the action of a compound’s mechanisms.

The new HTRF α-tubulin housekeeping kit is based on the TR-FRET immunoassay format and measures the endogenous level of α-tubulin in cell and tissue lysates.

Cisbio has prepared three application notes for you that include:
• Case studies for multi-parametric detection in the same cell lysate
• Demonstrations of kit adaptability to different species, buffers, cellular types, and cultures
• Evidence of this kit’s advantages over other kits

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LymphoTrack® Dx TRB Assay on MiSeq®

Invivoscribe has completed their CE-marked IVD LymphoTrack® Dx Assay suite with the addition of the LymphoTrack Dx TRB Assay.

The LymphoTrack Dx TRB Assay - MiSeq® is an in vitro diagnostic product intended to identify and track clonal T-cell receptor (TRB) gene rearrangements using next-generation sequencing (NGS) on the Illumina® MiSeq®. This assay will determine the frequency distribution of TRB Vβ-Jβ gene rearrangements in patients suspected of having lymphoproliferative disease.

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Early diagnosis of osteoporosis

New evidence: microRNA bone biomarkers can improve early diagnosis of osteoporosis.
First comprehensive attempt to model the cost-effectiveness of circulating microRNAs for bone fracture risk assessment in comparison with DXA and FRAX®.

Cost-utility analysis of fracture risk assessment using microRNAs compared with standard tools and no monitoring in the Austrian female population. E. Walter, H. Dellago, J. Grillari, H.P. Dimai, M. Hackl, Bone, Volume 108, 2018, pages 44-54. Click link for full-text publication.

The results demonstrate that the osteomiR™ kit can be a cost-effective alternative to established risk assessment strategies.

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Elabscience neuroscientific reagents

Are you working in the field of neuroscience? Please have a look at the high quality ELISA kits and antibodies from Elabscience for the study associated with the nervous system.

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Euro Diagnostica new in our portfolio

Bio-Connect Diagnostics is proud to inform you that we have become partner of Euro Diagnostica. We are now the distributor of Euro Diagnostica in The Netherlands. Euro Diagnostica provides clinical labs and physicians with tools to aid in diagnosis, prognosis, monitoring and treatment of inflammatory and related diseases. By offering high quality diagnostic assays.

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The distribution of VIROTECH Diagnostics products

VIROTECH Diagnostics has decided to partner up with Bio-Connect Diagnostics. We are now the exclusive distributor of VIROTECH Diagnostics products in The Netherlands. They provide infectious disease ELISA kits, and immunoblots.

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GeneProof MRSA PCR kit

Bio-Connect Diagnostics would like to inform you about launch of GeneProof's new product the MRSA PCR kit. The PCR kit is designed for methicillin-resistant Staphylococcus aureus detection by the real-time Polymerase Chain Reaction (PCR) method.

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The Only Internationally Standardized CE-IVD Assay for FLT3 Signal Ratio Mutation Analysis

The LeukoStrat CDx FLT3 Mutation Assay from Invivoscribe is a PCR-based in vitro diagnostic test designed to detect internal tandem duplications (ITD), tyrosine kinase domain (TKD) mutations (D835 and I836) and to determine the respective signal ratio (SR) values in the FLT3 gene. This assay amplifies genomic DNA extracted from mononuclear cells obtained from peripheral blood or bone marrow aspirates of patients diagnosed with acute myelogenous leukemia (AML).

Companion Diagnostics Novartis and Invivoscribe »»

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Revel the Mechanisms of Host Defense by Cross-regulation of TLR Responses

A recent Nature Immunology paper describes the epigenetic landscape that results from the integration of the inflammatory cytokines type I interferons and TNF.

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Elabscience antibodies available on our website

Elabscience provides a wide range of antibodies, including over 20,000 polyclonal and monoclonal antibodies, phospho antibodies, acetyl antibodies, tag antibodies, secondary antibodies, isotype antibodies, etc. All antibodies are strictly tested to ensure the purity and quality. Elabscience's antibodies can be applied in ELISA, WB, IHC, IP and ChIP.

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GeneProof Factor XIII V34L PCR kit

The GeneProof Factor XIII V34L PCR kit is designed to detect polymorphism of the F13A1 gene encoding the subunit A of FXIII factor by use of the real-time Polymerase Chain Reaction (PCR) method.

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Procollagen-III-peptide (PIIINP) ELISA kit

Bio-Connect Diagnostics would like to inform you about the launching of Cisbio's IVD P3NP-ELISA kit. The first ELISA P3NP CE-marked kit available on the market.

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NEW LeukoStrat FLT3 Assay - Available Now!

Invivoscribe has released their CE-marked LeukoStrat® FLT3 Mutation Assay 2.0. This in vitro diagnostic (IVD) product is intended for PCR-based ABI detection of FLT3 activating mutations in patients with acute myelogenous leukemia (AML).

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Introducing GeneProof

Bio-Connect Diagnostics is proud to introduce GeneProof and its products to the Benelux market. They are a biotechnology company operating in the field of molecular in vitro diagnostics of serious infectious and genetic diseases. Their portfolio includes PCR kits, DNA and RNA extraction kits, and nucleic acid extraction system. All GeneProof products are CE IVD certified.

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Mercodia Total GLP-1 NL-ELISA

We are proud to present the new Mercodia Total GLP-1 NL-ELISA, the first assay in their new chemiluminescent product line “Northern Lights”. The Total GLP-1 ELISA requires only 25 µL of human plasma and the dynamic range is 0.9-940 pmol/L.

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Artron Rapid Diagnostic Test Kits

Artron Laboratories Inc. is specialized in the production of high quality rapid lateral flow tests for the detection of fertility hormones, tumour markers, drugs of abuse, cardiac markers, infectious diseases, food safety, genetically modified organisms, and food safety.

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Cisbio HTRF®

HTRF®, is the premier TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) technology on the market. TR-FRET technologies such as HTRF® bring together the sensitivity of fluorescence with the homogeneous nature of FRET (Fluorescence Resonance Energy Transfer) and the low background of time resolution. HTRF® uses two fluorophores, a donor and an acceptor dye, that transfer energy when in close proximity to each other. This creates a homogeneous assay format in which bound and unbound partners do not need to be separated as fluorescence emission from the acceptor is generated only upon binding.

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CE-Marked NGS-Based LymphoTrack® Dx Assays

Invivoscribe has released four CE-marked LymphoTrack® Dx next-generation sequencing (NGS) assays used to detect T-cell receptor gamma (TRG) and immunoglobulin heavy chain (IGH) gene rearrangements. These in vitro diagnostic (IVD) test kits, validated for use with the Illumina MiSeq® and ThermoFisher Ion PGM™ instruments, comprise just a few of the CE-marked LymphoTrack Dx assays that Invivoscribe intends to release.

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Exclusive for Mercodia products

Bio-Connect Diagnostics B.V. has become the exclusive partner of Mercodia products in the Benelux. We have intensified our cooperation to offer you better service, good technical support and easier ways to order.

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FGF23 (C-terminal) ELISA - CE marked!

Biomedica Launches First CE Marked FGF23 ELISA Assay in Europe and Asia
Vienna, Austria, April 22, 2015 / B3C newswire / -- The biomarker specialists at Biomedica Immunoassays, announced the launch of the first CE marked FGF23 (C-terminal) ELISA assay which specifically detects both intact and C-terminal fragments of FGF23 in human serum and plasma. The FGF23 ELISA assay complements the existing Biomedica assays directed against chronic kidney disease - mineral and bone disorder (CKD-MBD) in a growing collection. The FGF23 ELISA assay will be an important tool for researchers investigating new biomarkers that could improve prediction of CKD progression, as well as discovery of new drug targets.

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Ghrelin EIA kits

Bertin Pharma offers a totally new set of assays that will allow any scientist to measure acylated and unacylated Ghrelin whatever the collection procedure. Those assays are called Easy Sampling because any blood sample collected can be used on any kind of protease inhibitors with or without acidification. While there is not yet a consensus on the collection procedure, we are quite confident that the scientific community will work toward this, especially if the biomarker is involved in clinical trials or later on in clinic. It is today largely accepted that a study involving Ghrelin should include both acylated and unacylated forms, while total Ghrelin is almost irrelevant.

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Introducing the Mercodia Glucagon ELISA – 10µL

The Mercodia Glucagon ELISA – 10µL is based on our very popular Glucagon ELISA, but requires an even lower sample volume. The need for high sample volumes in glucagon assays has for a long time limited the possibility of performing time-course studies of glucagon levels when working with rodents as a model animals.

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Next-Generation Sequencing products

We are excited to announce that Invivoscribe has expanded the portfolio of next-generation sequencing (NGS) products for both the Illumina MiSeq® and Life Technologies / Thermo Fisher Ion PGM™ platforms with the introduction of three additional assays which completes a suite of assays which allows testing of TRG and IGH:

• LymphoTrack® IGH Somatic Hypermutation Assay – PGM
• LymphoTrack® IGH + TRG Assay – PGM
• LymphoTrack® IGH + TRG Assay – MiSeq

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